SKIN+BONES

Organic Hydrolyzed Collagen Peptides

Claim supported: Supports skin hydration, elasticity, and dermal density with sustained effects after supplementation.

Wang Y, et al. (2025). The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study. Journal of Cosmetic Dermatology, 24(12), e70565. PMID: 41311286. DOI: 10.1111/jocd.70565

Key finding: 12 weeks of oral BCP supplementation produced lasting improvements in skin hydration, firmness, and dermal density, including through a 4-week washout period. Improvements associated with high hydroxyproline content and a low molecular weight distribution.
Study type: RCT, double-blind, placebo-controlled, 77 participants, 12 weeks.

Czajka A, et al. (2018). Daily oral supplementation with collagen peptides combined with vitamins and other bioactive compounds improves skin elasticity and has a beneficial effect on joint and general wellbeing. Nutrition Research, 57, 97–108. PMID: 30122200. DOI: 10.1016/j.nutres.2018.06.001

Key finding: Oral hydrolyzed collagen supplementation for 90 days produced a +40% increase in skin elasticity vs. placebo (p < .0001). Histological analysis confirmed improved collagen fiber organization and reduced solar elastosis.

Organic Camu Camu (Myrciaria dubia) Fruit

Claim supported: Exceptionally high whole-food vitamin C content with antioxidant, anti-inflammatory, and photoprotective activity.

Maqsood S, et al. (2025). Nutritional Composition, Pharmacological Properties, and Industrial Applications of Camu Camu: An Undiscovered Superfruit. Food Science & Nutrition, 13(6), e70331. PMID: 40417739. DOI: 10.1002/fsn3.70331

Key finding: Camu camu’s bioactive profile (vitamin C, polyphenols, flavonoids, anthocyanins, ellagic acid) contributes to metabolic, anti-inflammatory, antioxidant, and antibacterial activity. Bioavailability and beneficial activity surpass those of many other fruits.

Biffi MT, et al. (2025). Camu Camu hydroalcoholic extract with bioactive compounds, antitumor and photoprotective activity against UVB radiation. Journal of Toxicology and Environmental Health, Part A, 88(24), 1059–1072. PMID: 40653629. DOI: 10.1080/15287394.2025.2532777

Key finding: Camu camu extract demonstrated significant photoprotective activity against UVB radiation in cell models, with ascorbic acid content measured at 3,504 mg/100ml. The extract was not cytotoxic to normal cells while showing cytotoxic effects on tumor cells.

Organic Mangosteen (Garcinia mangostana) Fruit

Claim supported: Potent antioxidant and anti-inflammatory activity via xanthone compounds, with documented neuroprotective potential.

Thew HY, et al. (2025). A Systematic Review of Neuroprotective Effects of Mangosteen and its Xanthones Against Oxidative Stress and Inflammation. Planta Medica, 91(14), 786–801. PMID: 40845897. DOI: 10.1055/a-2665-2226

Key finding: PRISMA systematic review of 40 studies confirmed mangosteen extract and xanthones reduce oxidative markers, decrease pro-inflammatory cytokines, and modulate NF-κB and COX-2 pathways in neuroinflammation models.

Ortega YT, et al. (2025). Extraction of bioactive compounds from Garcinia mangostana L., using green technologies: a comprehensive analysis. Journal of Food Science and Technology, 62(11), 2031–2042. PMID: 41041503. DOI: 10.1007/s13197-025-06432-7

Key finding: Mangosteen is rich in phenolic compounds, anthocyanins, flavonoids, and isoprenylated xanthones with potent antioxidant and anti-inflammatory properties and applications across food, pharmaceutical, and cosmetic sectors.

Organic Tremella (Tremella fuciformis) Mushroom

Claim supported: Polysaccharides with hyaluronic acid-like water-retention properties and collagen-supporting activity promote skin hydration and wound healing.

Ma X, et al. (2021). A review on the production, structure, bioactivities and applications of Tremella polysaccharides. International Journal of Immunopathology and Pharmacology, 35. PMID: 33858263. DOI: 10.1177/20587384211000541

Paterska M, et al. (2024). Macrofungal Extracts as a Source of Bioactive Compounds for Cosmetical Anti-Aging Therapy: A Comprehensive Review. Nutrients, 16(16). PMID: 39203946. DOI: 10.3390/nu16162810

Key finding: Tremella fuciformis polysaccharides act as moisturizing agents, stabilize hyaluronic acid levels in skin, and exhibit anti-aging effects including antioxidant and anti-inflammatory activity.

Song GR, et al. (2026). Structural Elucidation and Moisturizing Potential of a Polysaccharide Derived from Tremella. Molecules, 31(2), 278. PMID: 41599327. DOI: 10.3390/molecules31020278

Key finding: Tremella fuciformis polysaccharide (TFP) was directly compared to hyaluronic acid (HA) as a moisturizing agent. TFP upregulated hyaluronic acid synthase expression in skin cells, supporting its mechanism as a natural HA-like hydrating compound.

Xu Z, et al. (2024). Cuttlefish ink-derived melanin nanoparticle-embedded tremella fuciformis polysaccharide hydrogels for the treatment of MRSA-infected diabetic wounds. International Journal of Biological Macromolecules, 277(Pt 4), 134342. PMID: 39111486. DOI: 10.1016/j.ijbiomac.2024.134342

Key finding: Tremella fuciformis polysaccharides (TFPs) form hydrogel frameworks with anti-inflammatory properties that promote wound healing, including collagen deposition, angiogenesis, and cell proliferation. Wounds repaired within 14 days in treated models.

Organic Ashwagandha (Withania somnifera) Root

Claim supported: Clinically demonstrated reduction in perceived stress, anxiety, and serum cortisol levels.

Arumugam V, et al. (2024). Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis. Explore, 20(6), 103062. PMID: 39348746. DOI: 10.1016/j.explore.2024.103062

Key finding: Meta-analysis of 9 RCTs (558 patients) showed significant reductions in Perceived Stress Scale (MD = −4.72), Hamilton Anxiety Scale (MD = −2.19), and serum cortisol (MD = −2.58) vs. placebo.

Organic Amla (Emblica officinalis) Fruit

Claim supported: Broad-spectrum antioxidant, anti-inflammatory, and collagen-supporting activity via a dense bioactive phytochemical profile.

Bhattacharyya J, et al. (2025). An Updated Review on the Anti-Inflammatory Potential of Phyllanthus Genus. Chemistry & Biodiversity, 22(9), e202402483. PMID: 40271556. DOI: 10.1002/cbdv.202402483

Key finding: Phyllanthus emblica (amla) demonstrates anti-inflammatory effects via reduction of pro-inflammatory cytokines, inhibition of COX-2, NOX, and LOX, and modulation of NF-κB, Nrf2, ERK/JNK, and MAPK signaling pathways.

Pratima H, et al. (2025). Phytochemical profile and hepatoprotective potentiality of Phyllanthus genus: a review. Journal of Pharmacy and Pharmacology, 77(2), 189–205. PMID: 38642916. DOI: 10.1093/jpp/rgae040

Key finding: Phyllanthus emblica contains lignans, alkaloids, terpenoids, flavonoids, and tannins, including gallic acid and quercetin. In vitro and in vivo studies confirm significant antioxidant and hepatoprotective potential.

BLOOD+GUT

Organic Maqui (Aristotelia chilensis) Berry

Claim supported: High-concentration anthocyanins with antioxidant activity via Nrf2 pathway modulation, cardiometabolic support, and anti-inflammatory effects.

Tiscornia C, et al. (2026). Maqui as a Chilean Functional Food: Antioxidant Bioactivity, Nutritional Value, and Health Applications. Antioxidants, 15(2), 204. PMID: 41750585. DOI: 10.3390/antiox15020204

Key finding: Maqui’s delphinidins modulate Nrf2-HO-1 and NF-κB pathways. Preclinical and early clinical evidence support cardiometabolic and nephroprotective effects, with improvements in glycemic control, lipid metabolism, oxidative stress, and endothelial function.

Organic Black Chia (Salvia hispanica) Seed

Claim supported: Rich source of omega-3 fatty acids and dietary fiber with anti-inflammatory, cardioprotective, and metabolic benefits.

Huang M, et al. (2024). The nutritional profile of chia seeds and sprouts: tailoring germination practices for enhancing health benefits—a comprehensive review. Critical Reviews in Food Science and Nutrition, 65(12), 2365–2387. PMID: 38622873. DOI: 10.1080/10408398.2024.2337220

Key finding: Chia seeds are rich in dietary fiber, omega-3 fatty acids, protein, and phenolic compounds, which contribute to antioxidant and anti-inflammatory effects and may improve glucose metabolism and dyslipidemia.

Pam P., et al. (2024). Chia seed supplementation and inflammatory biomarkers: a systematic review and meta-analysis. Journal of Nutritional Science, 13, e91. PMID: 39703891. DOI: 10.1017/jns.2024.70

Key finding: Meta-analysis of 4 RCTs (210 participants) showed chia consumption significantly decreased CRP (WMD: −0.64 mg/dL; p = 0.03), a primary marker of systemic inflammation.

Organic Mesquite (Prosopis pallida) Pods

Claim supported: High-protein, high-fiber whole food with nutritional composition supporting sustained energy and digestive health.

Mamone G, et al. (2019). Comparative analysis of protein composition and digestibility of Ceratonia siliqua L. and Prosopis spp. seed germ flour. Food Research International, 120, 188–195. PMID: 31000229. DOI: 10.1016/j.foodres.2019.02.035

Key finding: Prosopis spp. flour contains a more nutritionally adequate essential amino acid complement than carob and shows high digestibility during simulated gastrointestinal digestion, releasing large amounts of free amino acids. Confirmed as a high nutritional value, health-promoting food ingredient.

Organic Ginger (Zingiber officinale) Root

Claim supported: Modulates gut microbiota, reduces inflammation via pro-inflammatory cytokine suppression, and supports digestive function.

Che K, Wang C, Chen H (2025). Advancing functional foods: a systematic analysis of plant-derived exosome-like nanoparticles and their health-promoting properties. Frontiers in Nutrition, 12, 1544746. PMID: 40115388. DOI: 10.3389/fnut.2025.1544746

Key finding: Ginger-derived nanoparticles alleviate colitis by downregulating pro-inflammatory cytokines and modulating gut microbiota. Ginger’s bioactive components interact with mammalian cells and gut microbiota to enhance nutrient bioavailability and exhibit anti-inflammatory properties.

Organic Cordyceps (Cordyceps sinensis) Mushroom

Claim supported: Bioactive compounds, including cordycepin and adenosine, support cellular energy, anti-inflammatory response, and skin resilience.

Jędrejko M, et al. (2026). Current Evidence of Ergogenic and Post-Exercise Recovery Effects of Cordyceps Dietary Supplementation within Humans — A Narrative Review. Nutrients, 18(5), 781. PMID: 41829950. DOI: 10.3390/nu18050781

Key finding: Review of 5 human intervention studies found Cordyceps militaris supplementation showed improvements in aerobic performance parameters including maximal oxygen uptake (VO₂max), time to exhaustion, power output, and peripheral oxygen saturation during high-intensity exercise. Cordycepin is identified as a key bioactive compound.

Nguyen TQ, et al. (2025). Cordyceps-Derived Bioactive Gels: Therapeutic and Anti-Aging Applications in Dermatology. Gels, 11(1), 33. PMID: 39852004. DOI: 10.3390/gels11010033

Key finding: Cordyceps compounds (cordycepin, polysaccharides, adenosine) exhibit apoptosis induction, anti-inflammatory effects, and antioxidant properties that enhance skin resilience by scavenging reactive oxygen species and promoting collagen synthesis.

Organic Baobab (Adansonia digitata) Fruit

Claim supported: Dense prebiotic fiber, whole-food vitamin C, and bioactive compounds with antioxidant activity and glycemia-regulating potential.

Silva ML, et al. (2023). Adansonia digitata L. (Baobab) Bioactive Compounds, Biological Activities, and the Potential Effect on Glycemia: A Narrative Review. Nutrients, 15(9), 2170. PMID: 37432337. DOI: 10.3390/nu15092170

Key finding: Baobab contains phenols, flavonoids, proanthocyanins, tannins, carotenoids, vitamin C, and minerals (zinc, potassium, magnesium, iron, calcium). Demonstrated antioxidant, anti-inflammatory, analgesic, and antimicrobial activities with evidence of glycemia-regulating effects in animal and human trials.

PUMPKIN SEED PROTEIN (Unflavored + Cacao)

Organic Cold-Pressed Pumpkin (Cucurbita pepo) Seed

Claim supported: Complete protein with all 9 essential amino acids and exceptionally high mineral content, including magnesium, zinc, iron, and potassium.

Raza N, et al. (2026). Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights. Food Science & Nutrition, 14(2), e71480. PMID: 41625268. DOI: 10.1002/fsn3.71480

Key finding: Pumpkin seeds enhance immune function due to their mineral profile (magnesium, zinc, potassium, and iron). Their bioactive compounds (polyphenols, carotenoids, peptides) contribute to strong antioxidant and anti-inflammatory effects, validated as a functional food with cardiovascular, metabolic, and immune health benefits.

Organic Cacao (Theobroma cacao) Seed Powder + Seed Nibs

Claim supported: Exceptional dietary magnesium source with cardiovascular, cognitive, and gut microbiome benefits via polyphenol and flavanol activity.

Ross FC, et al. (2024). Potential of dietary polyphenols for protection from age-related decline and neurodegeneration: a role for gut microbiota? Nutritional Neuroscience, 27(9), 1058–1076. PMID: 38287652. DOI: 10.1080/1028415X.2023.2298098

Key finding: Cocoa flavan-3-ols are associated with cardiovascular benefits, cognitive function support, and brain-region-specific effects on memory formation. Polyphenols alter gut microbiota composition and are metabolized by different microbial species, linking cocoa consumption to the gut-brain axis.

Ditchfield C, et al. (2023). Can Chocolate Be Classified as an Ultra-Processed Food? A Short Review on Processing and Health Aspects. Foods, 12(16), 3070. PMID: 37628068. DOI: 10.3390/foods12163070

Key finding: Cocoa/cacao is rich in polyphenols, alkaloids, and amino acids. Studies demonstrate the benefits of regular consumption, including reduced cardiovascular risk, reduced oxidative and inflammatory burden, improved cognitive function, and maintained gut microbiota diversity.